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CORONADO, Calif.

Two senior Navy SEAL leaders and a senior medical officer received reprimands in connection with the February death of a SEAL trainee at the services school in Coronado, officials said this week.

Seaman Kyle Mullen, 24, died Feb. 4 after completing Hell Week, a strenuous 5-day training session that ends the first phase of the notoriously rigorous Basic Underwater Demolition/SEAL training course. The Navy describes BUD/S as among the most mentally and physically demanding training in the world.

The line-of-duty investigation into Mullens death, released by the service Wednesday, raises questions about how the Navy supervises trainees, who might be discouraged from reporting medical problems to instructors for fear of being dropped or rolled back in training.

More than half of Navy SEAL trainees dont complete the first phase of training.

Mullen was suffering from pneumonia and had a swimming-induced pulmonary edema, a condition in which water accumulates in the lungs during surface or underwater swimming, an autopsy found. SEAL trainees are susceptible to the condition due to the nature of their training they are sent in and out of the cold waters of the Pacific on the Silver Strand in Coronado, where the Naval Special Warfare Center is located.

The sailors heart was also enlarged, according to the autopsy. Mullen died of cardiac arrest caused by acute pneumonia. His enlarged heart was a contributing factor, the autopsy said.

The Navy medical examiner did not test for drugs. However, Navy medical experts who reviewed the findings noted in the report that performance-enhancing drugs steroids and human growth hormone were found in his belongings. Had he taken them, they could have contributed to his heart condition.

After discovering the drugs, Naval Special Warfare launched an investigation and found about 40 other SEAL trainees had used performance-enhancing drugs, the New York Times reported in August.

Mullen had already been diagnosed with the pulmonary edema three weeks before Hell Week, according to the report.

But several of Mullens classmates told investigators that he struggled to breathe and was spitting up blood during Hell Week in the days before his death. Although he was coughing up blood and pink foam, Mullens classmates said the sailor didnt want to seek medical care because he didnt want to roll back in training. Mullen had already been held back once due to heatstroke, the report said.

Mullens legs also began to swell during the week, something the Navy told trainees was normal during Hell Week. Mullen gained 22 pounds during Hell Week, the report said.

Navy medical personnel gave Mullen supplemental oxygen on Feb. 3 and the morning of the day he died, the report said.

Mullen finished Hell Week the morning of Feb. 4 and was taken to his barracks room in a wheelchair to recover. A medical officer on duty recommended calling 911, but it did not happen. When Mullen became unresponsive in his room about 90 minutes later, paramedics were called. A Gatorade bottle full of the pink fluid hed been coughing up for hours was found next to him, the investigation said.

He died at Sharp Coronado Hospital.

The report concludes that Mullen died in the line of duty and not due to his own misconduct.

The incident has already sparked changes in how the health of sailors is monitored during Hell Week, the Associated Press reported, and led to expanded testing for performance-enhancing drugs.

Capt. Brian Drechsler, the commanding officer of the Naval Special Warfare Center, received a reprimand letter as a result of the investigation, according to a Naval Special Warfare spokesperson. Capt. Brad Geary, the former commander of Naval Special Warfares Basic Training center, and a senior medical officer also received letters. Geary has since moved on to another job in a routine rotation. None of the officers were removed from their jobs, and the reprimands were non-punitive, the spokesperson said.

A separate command investigation into Mullens death is ongoing, the spokesperson said, and the administrative actions against the officers will be reviewed.

A review of Hell Week in consultation with 87 SEALs was included in the report. The vast majority of those surveyed said theyd encountered conditions as challenging as Hell Week during real-world SEAL operations.

Originally posted here:

Navy SEAL leaders reprimanded over trainee's death in 'Hell Week' - Los Angeles Times

Crops often face harsh growing environments. Instead of using energy for growth, factors such as disease, extreme temperatures, and salty soils force plants to use it to respond to the resulting stress. This is known as the growth-stress response trade-off. Now, a group of researchers from Nagoya University has discovered a previously unknown pathway that regulates whether a plant uses its resources for growth or stress tolerance. This discovery could enable the stress response to be controlled under agricultural conditions, increasing crop yields. They published the findings in the journalScience.

A research group, led by Professor Yoshikatsu Matsubayashi and Assistant Professor Mari Ohnishi of the Graduate School of Science at Nagoya University in Japan, investigated the role of hormones and their receptors in the plant stress response. They focused on three receptors for which the corresponding hormone had not yet been identified. Using thale cress (Arabidopsis thaliana), a small flowering plant, they discovered the PSY family, which functions as a hormone, binding to these receptors and mediating the switch between the stress response and growth.

When the researchers investigated the pathway involved, they made an unexpected discovery. Usually, receptors and hormones function like locks and keys, with the hormone (in this case, a peptide PSY hormone) acting as a key that is necessary to start a biological process. However, in this study, plant cells that did not produce PSY nonetheless had an active stress response. Therefore, this suggests that instead of activating the stress response, the presence of the PSY key in the receptor lock keeps it switched off.

To test the nature of stress responses, the researchers grew plants under extremely stressful conditions using heat, salt, and also infected them with bacteria. Plants that were either deficient in PSY receptors or were continuously fed the hormone PSY failed to respond adequately to stress, resulting in reduced survival. The scientists concluded that stressed plants stop releasing PSY, the absence of which induces stress response genes.

To explain this phenomenon, the researchers proposed a mechanism in which damaged cells reduce the concentration of PSY hormones in the cell layers next to the damaged sites. This lack of PSY triggers the stress response. Importantly, this may explain why even damaged plants can send messages. Rather than using their limited resources to create a new signal, an impaired plant cellmay instead stop the release of the PSY hormone, activating the stress response. Such a mechanism would balance stress tolerance with associated energy costs. As a result, even under the most stressful environmental conditions, plants can still grow by managing their limited resources.

Most of the mechanisms found in Arabidopsis are found in other plants. Therefore, our results apply to all crops, explained Matsubayashi. This mechanism makes it possible to artificially control the balance between stress tolerance and yield, which is a trade-off relationship. In recent years, an increasing number of crop plants have been grown in plant factories. When crops are grown indoors, it is a low-stress environment and the stress response system that is needed to withstand the fluctuating natural outdoor environment is not always necessary. Generating cultivars with reduced PSY receptor activity in plant factories may lead to higher yields in these controlled environments.

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Discovery Of Family Of Hormones May Be Key To Increased Crop Yields - Eurasia Review

This comprehensive Report on Protein Therapeutics Market provides real information about the statistics and state of the global and regional market. Its scope study extends from the market situation to comparative pricing between the main players, spending in specific market areas, and profits. It represents a comprehensive and succinct analysis report of the main competitor and price statistics with a view to helping beginners establish their place and survive in the market. In addition, it also focuses on the market overview for the coming period from 2022 to 2030. This proved to be a great help for entrepreneurs. This detailed market research is heavily based on information received during interviews with key leaders, research, and innovative resources.

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In addition to the information presented in this report on the Protein Therapeutics Market, it includes financial losses incurred as a result of COVID-19. It also explains how the most important business sectors in the market are coping with the epidemic and how to get out of it. This market report is a way to present accurate information on company profiles and competitiveness analyses in an orderly manner. It anticipates competition in the market for the planned period from 2022 to 2030. This Protein Therapeutics Market study also looks at industry channels and performance rates to help key players stay ahead of the competition.

The major players covered in Protein Therapeutics Market:

Abbott Laboratories Amgen Inc. Baxter International Inc. Eli Lilly And Company F. Hoffmann La Roche Ltd Johnson and Johnson (Janssen Pharmaceuticals) Merck and Co. Inc. Novo Nordisk AS Pfizer Inc. Sanofi

Market Segmentation: By Type

Monoclonal Antibodies Insulin Fusion Protein Erythropoietin Interferon Human Growth Hormone Follicle Stimulating Hormone

Market Segmentation: By Application

Metabolic Disorders Immunologic Disorders Hematological Disorders Cancer Hormonal Disorders Genetic Disorders Others

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Market Segmentation: By Geographical Analysis

The Middle East and Africa (GCC Countries and Egypt)North America (the United States, Mexico, and Canada)South America (Brazil etc.)Europe (Turkey, Germany, Russia UK, Italy, France, etc.)Asia-Pacific (Vietnam, China, Malaysia, Japan, Philippines, Korea, Thailand, India, Indonesia, and Australia)

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Key questions answered in the report include:

Who are the key market players in the Protein Therapeutics Market?Which are the major regions for dissimilar trades that are expected to eyewitness astonishing growth for the Protein Therapeutics Market?What are the regional growth trends and the leading revenue-generating regions for the Protein Therapeutics Market?What will be the market size and the growth rate by the end of the forecast period?What are the key Protein Therapeutics Market trends impacting the growth of the market?What are the major Product Types of the Protein Therapeutics Market?What are the major applications of Protein Therapeutics Market?Which Protein Therapeutics Market Services technologies will top the market in the next 7 years?

Table of Contents:

Global Protein Therapeutics Market Research Report 20222030

Chapter 1 Protein Therapeutics Market OverviewChapter 2 Global Economic Impact on IndustryChapter 3 Global Market Competition by ManufacturersChapter 4 Global Production, Revenue (Value) by RegionChapter 5 Global Supply (Production), Consumption, Export, Import by RegionsChapter 6 Global Production, Revenue (Value), Price Trend by TypeChapter 7 Global Market Analysis by ApplicationChapter 8 Manufacturing Cost AnalysisChapter 9 Industrial Chain, Sourcing Strategy and Downstream BuyersChapter 10 Marketing Strategy Analysis, Distributors/TradersChapter 11 Market Effect Factors AnalysisChapter 12 Global Protein Therapeutics Market Forecast

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New Technology Developments in Protein Therapeutics Market to Grow during Forecast year 2022-2030 | Abbott Laboratories, Amgen Inc., Baxter...

The Tallest Man Living is one of Guinness World Records most iconic titles.

Tallness has long been a sign of greatness and success in history. The Chinese held it desirous for men to betall, wealthy, and handsometallness coming nominally first. Our times have seen several men of towering stature, whose height has garnered celebrity, steep challenges, and in some cases romance.

Here, well peruse three of the tallest men ever recorded who lived in recent times, or are still living, whove claimed several Guinness World Record titles.

The current title for the Tallest Man Living is held by Sultan Ksen, 39, from Turkey, who, at age 9, became the first man over 8 feet to be measured by Guinness in over 20 years. Guinness has confirmed only 10 reliable cases of men reaching 8 feet in history.

Born on Dec. 10, 1982, Ksen did not experience his growth spurt until age 10. The rest of his family, including his parents, were of average size.Due to his height, he didnt finish school and instead he began working as a farmer to support his family.

Ksen towered a breathtaking 8 feet, 1 inch (246.5 cm) tall when he was measured in February 2009 and claimed the title for the first time. Two years later, at age 26, he broke this record, measuring 8 feet, 2.8 inches (251 cm).

Ksens humongous height was caused by a condition called pituitary gigantism where there is an overproduction of growth hormone in the pituitary gland. This resulted in his hands growing to an incredible 11.22 inches (28.5 cm) from the wrist to the tip of the middle finger, and setting the record for the Largest Hands on a Living Person.

He cites some advantages of being so tall, such as being able to help his mom replace broken lightbulbs and hang curtains. He is a basketball fan and can slam dunk without his feet leaving the ground, though he was unable to play ball in school because he was too tall.

Some of the disadvantages of his height include finding clothes and shoes that fit his lanky limbs. Ksens left foot measures 1 foot, 2.4 inches (36.5 cm), while his right measures 1 foot, 2.0 inches (35.5 cm) in length. Its also terribly difficult for Ksen to fit in a car.

Thankfully, after gaining exposure through Guinness, the gentle giant received revolutionary gamma knife surgery from the University of Virginia on the tumor affecting his pituitary gland, which stopped him from getting any taller.

Ksen hoped his fame would lead to his eventually finding a wife, which it did in 2013 when he married Syrian-born Merve Dibo, who is 9 years his junior, whom hemet through a mutual friend. As fate would have it, the couple parted ways in 2021, reportedly because of a language barrier.

Prior to Ksen, the title holder of the Tallest Man Living was Bao Xi Shun, a goat herder from Chifeng, Inner Mongolia. Born in 1951, by his own account he remained normal in height until the age of 16. He then served in the Peoples Liberation Army for three years before returning to Inner Mongolia to live with his mother.

He claimed the title of Tallest Man Living in 2005, then measuring a knee-wobbling 7 feet, 9 inches (236 cm), towering 3 inches above former Chinese pro basketball player Yao Mings 7feet, 6inches.

Baos tallness resulted from anautoimmune condition called rheumatism, which can cause pain and inflammation in the joints and connective tissues of the body.

He is famous for reportedlyhelping save the lives of two dolphins inDecember 2006 by removing shards of plastic from their stomachs.Bao allegedly used his 3.47-foot- (1.06 meter-) long arms to reach into the dolphins stomachs to retrieve the sharp objects with his hands.

The herdsman, now 70, is typically shown in photographs donning traditional Mongolian dress at cultural events or his wedding.The towering Mongolian married Xia Shujuan, asaleswoman, on March 24, 2007, and they had a son together the following year.

Last but certainly not least, the late Illinoisan Robert Wadlow is still the titleholder of the Tallest Man Ever.

Wadlow was born an average-size baby on Feb. 22, 1918, weighing 8.7 pounds (3.85 kg). His two parents were also of average size, as were his four younger siblings.

Wadlow started to shoot up from there onward. At age 5, he measured a staggering 5 feet, 4 inches (1.63 meters), and was already wearing clothes intended for teenagers. By the age of 8, hed surpassed his 5 foot, 11 inches (180.3 cm) dad,Harold F. Wadlow, in height, and was even able to carry him up the stairs of their family home.

Wadlows height caused him a number of medical issues which only worsened as he grew older and taller.

He endeavored to participate in the same activities as his peers and became a Boy Scout at the age of 13. This required him to get a custom-made uniform, tent, and sleeping bag.

He garnered the title of the Tallest Teenager Ever at age 16, when he reached 8 feet, 0.5 inches (2.45 meters). He graduated from high school in 1936 and then enrolled in college to pursue a career in law.

Later that year, Wadlows soaring height led him to fame, and he embarked on a tour with the hugely popular Ringling Brothers Circus.

When asked in a radio interview if he was bothered by so many people staring at him, he answered, according to Guinness, No, I just overlook them.

Doctors examined Wadlow and determined that his exceptional size, likeKsens, resulted from pituitary gigantism causing excessive levels of human growth hormone. But unlike Ksen, Wadlow never received treatment to stop it.

The mild-mannered American was last measured on June 27, 1940, then stretching a staggering 8 feet, 11.1 inches (2.72 meters) talla record that hasnt been broken to this day.

Wadlow has claimed other records, including the Largest Feet Ever, his tootsies measuring a jaw-dropping 18.5 inches (47 cm) longenough to fill a US size 37AA. Back then, his shoes cost as much as $100, equal to about $1,700 in todays currency.Additionally, he boasted the Largest Hands Ever, with his measuring 12.7 inches (32.3 centimeters) from the wrist to the tip of the middle finger.

But Wadlow also had difficulty getting around. He wore leg braces and used a walking stick. It was his legs that eventually caused his premature death at age 22, on July 15, 1940. He died in a hotel in Manistee, Michigan, from a septic blister on his right ankle caused by his brace, which had been poorly fitted just a week earlier.

In 1986, this human being of unsurpassed stature was honored with his own life-sized statue, which was erected on College Avenue in Alton, opposite the Alton Museum of History and Art. Meanwhile, a number of life-size likenesses of the herculean American continue to stand in museums across the world.

Share your stories with us at emg.inspired@epochtimes.com, and continue to get your daily dose of inspiration by signing up for the Inspired newsletter at TheEpochTimes.com/newsletter

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3 of the World's Tallest Men Ever Recorded Lived in Our DayAnd Some Are Still Towering Over Us Today - The Epoch Times

The first thing you notice about Lionel Messi, quite possibly the greatest soccer player of all time, is that he looks basically like a normal guy. In the post-Beckham era of the Uncannily Handsome Footballer, when it feels like every great player is ridiculously good-looking, Messi is conspicuously nonconforming, standing a diminutive 5'6", squat and thick-necked and illogically pale, sporting a scruffy beard that only goes so far toward obscuring the distinct unchisel of his jawline and a hair-style that can only be described as Supercuts. The second thing you notice about Messi is that his name sounds an awful lot like messiah. The third thing you notice is that he plays like God. Which is why it was so jarring, last week, when he announced that this World Cup, his fifth, will be his last. Fans around the world turned their thoughts to life after Messi, and the position hell one day take among the games saints.

When thinking about Messis legacy, its worth remembering his origins. The son of a steelworker from Rosario, he was discovered as a prodigious 13 year old by Barcelonas scouts, who persuaded his father to sign a contract on a napkin and whisked his still-tiny son off to the clubs famed academy. Lionel struggled with a growth-hormone deficiency, but with a combination of the clubs medical care, tactical education, and his own preternatural skillset, he soon bloomed into the kind of phenomenon that even a club as fabled as Barcelona had never seen. After he made his senior debut, aged 17, the club proceeded to win 10 Spanish league titles and four Champions League trophies. Messi scored a club record 474 goals, many of them casually sublime. Indeed, deep into what shouldve been the autumn of his career, he was still scoring outrageous goals at an outrageous rate. It seemed like he might go on forever.

And then, suddenly, it was over. The club, reckless in its spending, teetered toward insolvency, and had to sell its favorite son in August 2021. With tears at his farewell press conference, Messi was offloaded to Paris Saint-Germain, the superclub bankrolled by the Qatari royal familya place where insolvency will never be a concern, and where, for perhaps the first time in his adult life, Messi foundered at the club level. In his first season playing in Paris alongside fellow megastars Kylian Mbappe and Neymar, he showed flashes of genius, but by his celestial standards it was a barren year. The joy that made him appear a demigod was gone, leaving Lionel to seem merely mortal.

Was his story winding down? It was not. With the World Cup around the corner, he now looks like a player reborn, scoring delightful free kicks, leading Paris Saint-Germain in assists, and looking rejuvenated for Argentina as well. He seems like his old self, which is to say: perhaps the greatest ever.

Like all great sporting argumentsJordan or LeBron, Federer or Nadalfootballs GOAT debate will reign eternal. Plausible arguments can be made for Pele, Maradona, Messi, or Ronaldo. So whether you consider Messi to be the best footballer of all time is a matter of personal preferencebut that he is the most famous player of all time is an indisputable fact. If you have never seen even a single minute of footballeven if you couldnt pick Messi out of a lineup of three men, all of whom were himyou know his name. You have heard it tossed about gleefully, chanted solemnly as incantation, cried out in religious ecstasy. It means Barcelona, it means Argentina, it means the World Cup, it means football in the modern era. Because to witness Messi is to witness a kind of dream, surreal and grand and moving, which is what modern football at its best has proven itself capable of producing.

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How Will the World Cup Shape Lionel Messis Legacy? - GQ

Legendary broadcaster Bob Costas on his comeback to MLB postseason series in 22 years

Emmy Award-winning sportscaster Bob Costas will make his return to the MLB postseason series in the American League Division Series for the first time since 2000. Costas will cover the ALDS between the New York Yankees and the Cleveland Guardians in the postseason.

In an interview with "The Athletic," the 70-year-old spoke about his return to broadcasting in the ALDS, saying:

Costas continued:

Costas will join Ron Darling and sideline reporter Lauren Shehadi to make his first appearance in the MLB postseason since the series between the Yankees and Seattle Mariners 22 years ago. He also signed a new deal last year to host the NLCS studio show. The veteran will also serve as the TBS studio host for the 2022 ALCS after his long-awaited return.

Former MLB legend Mark McGwire admitted to using PEDs in an interview with Costas in 2010. McGwire revealed that he took steroids before hitting a then-record 70 homers in 1998, with Sammy Sosa at 66. He also revealed that he used a human growth hormone before his retirement in 2001.

After the interview, Bob Costas defended the star, controversially saying that, despite the wrongdoing, he was a "nice" and "sincere" guy. He said:

McGwire won two World Series championships in his career, with Oakland in 1989 and the St. Louis Cardinals as a coach in 2011. He made it to 12 All-Star games, while winning the AL Rookie of the Year in 1987, with three Silver Slugger awards and one Gold Glove award.

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"It isnt quite like playing, but its the closest thing to it. You remember every pitch" - Legendary broadcaster Bob Costas on his comeback...

Published: Published Date - 11:42 PM, Fri - 14 October 22

Hyderabad: The article is in continuation to the last article about chemical coordination and integration in the human body. Today, lets discuss the functions of the hypothalamus and the pituitary gland. The information can be handy for the upcoming exams.

However, the hormones produced by hypothalamus are of two types, the releasing hormones (which stimulate secretion of pituitary hormones) and the inhibiting hormones (which inhibit secretions of pituitary hormones).

For example, a hypothalamic hormone called Gonadotrophin releasing hormone (GnRH) stimulates the pituitary synthesis and release of gonadotrophins. On the other hand, somatostatin from the hypothalamus inhibits the release of growth hormone from the pituitary. These hormones originating in the hypothalamic neurons pass through axons and are released from their nerve endings. These hormones reach the pituitary gland through a portal circulatory system and regulate the functions of the anterior pituitary. The posterior pituitary is under the direct neural regulation of the hypothalamus.

Pituitary GlandThe pituitary gland is in a bony cavity called sella tursica and is attached to hypothalamus by a stalk.It is divided anatomically into an adenohypophysis and a neurohypophysis. Adenohypophysis consists of two portions, pars distalis and pars intermedia.

The pars distalis region of pituitary, commonly called anterior pituitary, produces growth hormone (GH), prolactin (PRL), thyroid stimulating hormone (TSH), adrenocorticotrophic hormone (ACTH), luteinizing hormone (LH) and follicle stimulating hormone (FSH). Pars intermedia secretes only one hormone called melanocyte stimulating hormone (MSH).

However, in humans, the pars intermedia is almost merged with pars distalis. Neurohypophysis (pars nervosa) also known as posterior pituitary, stores and releases two hormones called oxytocin and vasopressin, which are actually synthesised by the hypothalamus and are transported axonally to neurohypophysis.

Over-secretion of GH stimulates abnormal growth of the body leading to gigantism and low secretion of GH results in stunted growth resulting in pituitary dwarfism. Excess secretion of growth hormone in adults especially in middle age can result in severe disfigurement (especially of the face) called Acromegaly, which may lead to serious complications, and premature death if unchecked. The disease is hard to diagnose in the early stages and often goes undetected for many years, until changes in external features become noticeable.

To be continuedBy

Dr. Modala Mallesh

Subject ExpertPalem, Nakrekal, Nalgonda9989535675

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Understand the different functions of pituitary gland - Telangana Today

Often, you hear the word inflammation and think of something terrible. But truthfully, your body experiences some pro-inflammatory effects. For instance, when you get sick. A massive release of white blood cells is released to attack the virus, which produces inflammation.

Or when muscles break down, they produce microtears on your muscles that produce inflammation caused by your training. The inflammation created acts as a signal to release hormones that rebuild muscles. Again, this is a perfectly normal post-training workout response.

The inflammation process is how your muscles repair. For example, when you work out, you create micro-tears in your muscles, stimulating and activating the inflammatory process. This inflammation is good. It is pro-inflammatory. Importantly, this inflammation signals the release of growth hormone, testosterone, and protein synthesis. These two hormones are responsible for repairing your muscles. And protein synthesis uses amino acids to rebuild them.

Because these hormones are highly sensitive in the first hours of post-training, it is best not to interrupt the process. So, avoid painkillers like ibuprofen, as well as eating vegetables.

So nutritionally speaking, consuming protein and carbs like granola immediately following exercise is the best option. It helps with protein synthesis for muscles to rebuild and replenish energy in a big way. But hold off on the veggie consumption for now. Antioxidants are present in vegetables. And antioxidants are also anti-inflammatories.

So, after a workout, avoid eating vegetables for a few hours so it does not interfere with the muscles pro-inflammatory response. Wait until lunch or dinner so they can help naturally reduce and clear the inflammation after the hormonal release is finished. Inflammation tends to linger, and veggies are a great way to flush it out.

Lets make it easy to understand and put it into one category. Stress is stress. The body determines it by what is happening inside. Acute inflammation is a positive thing. The problem is when inflammation becomes chronic and does not subside. When inflammation lingers too long, or youre experiencing too much of it, it makes it more difficult for muscles to repair, grow, become stronger, and function well.

For example:

The production of growth hormone and testosterone is suppressed when the body is under constant stress. Additionally, protein synthesis is inhibited. As a result, the bodys ability to repair and rebuild are diminished; therefore, muscles arent entirely recovered and restored. In turn, this causes your muscles to feel exhausted, weak, and prone to injury.

Exercise and training are powerful inflammatory stimulants. However, inflammation is a bit of a double-edged sword. You need it to grow and signal the proper process to make you stronger. But on the other hand, constant inflammation is detrimental. You want the inflammatory process to do its job and not get out of control to be a problem.

So, if you understand how inflammation works, you can use it to your advantage to recover faster and become stronger.

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Is Inflammation Good for Muscle Growth? And Does it Help to Eat Your Protein Before Your Vegetables? - STACK

We recently came across a debate on Reddit about Nugenix Total T reviews. A middle-aged man who'd apparently used Total T for 6 months was ranting about how the product didn't work for him. He said that he was extremely disappointed and that it was a waste of money.

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There were some new accounts that were fiercely defending the product and claiming that it had worked wonderfully for them.

We have been reviewing dietary supplements for over 3 years now and have come to the conclusion that most of these products are nothing but placebo pills. But when a product is marketed so well and has such good reviews, it is hard not to get tempted to try it out.

That is why we decided to take a closer look at this particular testosterone booster to see if it was really as ineffective as this man claimed.

What is Nugenix Total T?Nugenix Total T is a testosterone booster that claims to help in boosting energy levels, improve sex drive, and help in muscle growth. The company has been around for quite some time now and has a range of men's health products.

There's Nugenix Total T Maxx, a vitality booster, and even a free testosterone booster.

Testosterone boosting supplements are nothing novel. There's enough clinical evidence to say that testosterone levels in men have been declining every passing year.

Researchers attribute this to everything from environmental toxins to microplastics. But the fact is that your grandpa probably had double the T in his veins at your age, that you do now.

That's why TRT is a billion-dollar industry. But, a lot of people, us included do not subscribe to the idea of pinning exogenous testosterone for the rest of our lives.

That's why natural testosterone boosters like Total T, sell like hotcakes. You see, everyone wants to bump up their T levels with a pill. But, the question is - do these pills work?

How does Nugenix Total T work - The claimsNugenix Total T claims to offer the whole bouquet of benefits one associates with increased testosterone levels including lean muscle mass, sexual health, reduced body fat, fewer instances of erectile dysfunction, and energy levels.

Why, if we weren't aware that we are reading about a testosterone boosting supplement, we'd be mistaken that this was in fact an advert for a TRT clinic.

Lean Muscle mass tissueThe amount of muscle mass that your body can produce and sustain is inversely proportional to your age. So as you get older, it becomes increasingly difficult to put on and maintain muscle mass.

If you are over the age of 30, you have probably noticed that you are not as strong as you used to be and that it takes a lot more effort to stay in shape or even just get in shape. That can be attributed to your testosterone levels which have probably gone down by 1% every year since you turned 30.

Nugenix claims that their supplement can help in boosting muscle mass and strength by naturally increasing your testosterone levels.

Increased strengthThe amount of muscle mass that you have is not the only thing that contributes to your strength. Testosterone also plays a role in how strong those muscles are.If you have more testosterone, your muscles will be able to generate more force and help you lift heavier weights.

Nugenix Total T claims that it can make you stronger. If you are a middle-aged man, who's just hit a plateau in the gym, then this claim will definitely interest you.

Increased sex driveOne of the telltale signs of low testosterone is a loss in libido. Testosterone is the hormone that's responsible for your sexual urges. So, it stands to reason that if your T levels are down, so is your sex drive.

You just do not feel the urge to indulge in sexual activity anymore. Total T can apparently boost testosterone production to the extent that it has a positive influence on your sexual health.

Confidence and energy levelsAs your Testosterone levels increase, you will notice a difference in your mood. There's a marked improvement in the way you feel, you approach tasks. That's because Testosterone also happens to be this potent neurosteroid that offers all these benefits.

And Nugenix claims that their supplement can help in boosting your confidence and energy levels by increasing your serum testosterone levels and your free testosterone levels. Most testosterone supplements do not even affect your free testosterone levels.

So this claim from total t testosterone booster actually came across as a surprise.

Ingredients in Nugenix Total TThe first thing that we always check when reviewing a dietary supplement, is the list of ingredients.

This gives us an idea of how effective the product is likely to be.

Nugenix contains the following ingredients: B-Vitamins - B6 & B12 Minerals - Zinc, Boron Amino acid - L-Citrulline Malate Herb - Eurycoma Longifolia & Fenugreek

So, there are some interesting things in there. There's L-Citruline Malate which is a popular ingredient in pre-workout supplements.

It's an amino acid that's known to improve blood flow and increase nitric oxide levels in the body.

This can lead to better pumps in the gym. But, there's no clinical evidence to show that it can boost T.

The minerals Zinc & Boron are known to be important for Testosterone production.

Boron, in particular, is a micronutrient that's known to increase free testosterone levels in the body. However, the doses of these minerals in Nugenix are pretty low and are unlikely to offer any benefit.

The herbs too, have some interesting properties. Fenugreek is known to be a popular ingredient in Testosterone boosters. It's known to increase free testosterone levels and also has the added benefit of lowering SHBG (sex hormone binding globulin) levels.

Eurycoma Longifolia or apple fruit extract is another herb that's often used in T-boosters. It's known to be a potent aphrodisiac and is also thought to increase testosterone levels.

However, the doses are so minuscule that they are unlikely to offer any benefit.

So, on the whole, the ingredient list is not too impressive. There are some good ingredients in there but the doses are pretty low and are unlikely to offer any benefit.

Does Nugenix Total T work?The reason why we always review the ingredient list and then correlate it with clinical studies is that manufacturers are able to get away with a lot of lies and false claims.

The same is the case with Nugenix.

They have made some bold claims, which sadly have little or no clinical evidence to back them up.

Here's what we think. The ingredients are under dosedAs we said, there are some good ingredients that we consider to be the gold standard for anyone who's suffering from low testosterone levels. There's Zinc, Boron, Fenugreek, and Eurycoma Longifolia.

All of these ingredients have been clinically proven to increase testosterone levels. However, the doses are way too low for them to offer any benefit.

The doses are so low that they are unlikely to increase your testosterone levels by even 1%. Only if you are deficient in one of these minerals in the first place, may you see a small increase in your testosterone levels.

Ineffective ingredients for cosmetic appealThe other ingredients like B-Vitamins and L-Citrulline Malate are not going to have any effect on your testosterone levels.

It may produce some other benefits like improving blood flow and energy levels but not testosterone.

The doses are also very low for them to have any significant effect.

This is something that supplement companies do to make their products look more impressive. They include ineffective ingredients in their product, which actually does nothing other than increase the price of the product. L-Citrulline will convert into Arginine in your body and improve blood flow, which can lead to better muscle pumps.

That may fool some users into thinking that the product is working but it doesn't actually increase testosterone levels.

Nothing to boost free testosterone levels as claimedOne of the claims that they make is that Nugenix Total T can increase free testosterone levels and not just total testosterone. For those who are new to this, free testosterone is the percentage of testosterone that is bioavailable for use.

It's not bound to SHBG (sex hormone binding globulin) and can be used by your body for various functions.

Theoretically, this sounds true because some of the ingredients like Fenugreek and Eurycoma Longifolia are known to decrease SHBG levels in the body. This results in more testosterone being available for use.

But the letdown is the dosage. The doses of these ingredients are way too low for them to have any significant effect. Also, if Total T could increase your free testosterone levels, why do they sell another nugenix free testosterone booster?

Click here to Buy the Best Testosterone Boosters

Nugenix Total T CostAt $69.99 for a month's supply, Nugenix Total T is probably one of the most expensive T-boosters on the market.

For a lower price, you can get TestoPrime which actually has clinically effective doses of all its ingredients and is also one of our top-rated testosterone boosters.

Nugenix Total T review - Final ThoughtsNugenix Total T in our opinion is a let down. They obviously have a strong marketing team because we see their adverts everywhere.

But when it comes to the product, it's just not good enough.

It doesn't have clinically effective doses of its ingredients and is also very expensive. We would recommend that you give this one a miss and go for something else.There are three potent and clinically backed testosterone boosters that we would recommend.

#1 - TestoPrime - Our top rated T-booster with potent ingredients at clinically effective doses

Most testosterone boosters sold on the internet shy away from offering anything more than a template guarantee. But TestoPrime is the only T-booster that comes with a lifetime money-back guarantee.

If you don't see any results with TestoPrime, you can return the empty bottles and get a full refund. What does that tell you? For us, it shows that the company is very confident about the results their product can offer.

TestoPrime contains 12 clinically backed ingredients at optimal doses to help increase your serum and free testosterone levels.

Why TestoPrime is better than Nugenix Total T?There are two things that separate a quality testosterone booster supplement from an average one. The dosage of the ingredients and the quality of the ingredients.In our opinion, Nugenix Total T fails on both fronts.

The doses of the ingredients are way too low for them to have any significant effect. And some of the ingredients included are not going to have any impact on your testosterone levels.

On the other hand, TestoPrime is the strongest testosterone booster supplement on the market. It contains doses of all its ingredients that are clinically backed to help increase testosterone levels in your body, totaling almost 12 grams per dose.

The top 3 benefits of using TestoPrimeUsers who have used TestoPrime for a few months have claimed a total transformation in their lives. But we are going to limit it to the top three benefits here.

TestoPrime can help increase your energy levels and staminaIf you are someone who is looking for a safe and natural way to boost their energy levels, look no further than TestoPrime. The ingredients present in TestoPrime have all been clinically backed to support energy production in your body. You will gain muscle a lot easierIf you lift iron, get ready to see some serious gains. TestoPrime can help increase the level of nitrogen retention in your body, which is essential for protein synthesis and building muscle mass. You will notice an improvement in your sex lifeThe testosterone boosting effects will also extend to your love life. Testosterone is not only responsible for giving you those gains in the gym but also plays a vital role in regulating your sexual health.

If you have been experiencing erectile dysfunction more often, then your testosterone receptors in the penile tissue might be affected. This will help restore it.

TestoPrime CostDespite the huge difference in the potency and the ingredients, TestoPrime is actually priced lower than Nugenix Total T.

A bottle of TestoPrime that will last you a month costs $59.99. You can save money by opting for the 3-month package which cost $177.00 and gets you two bottles for free. Keeps getting better, doesn't it?

TestoPrime - Final thoughtsIf you are looking to increase your testosterone levels naturally, this is the first product you should go for. TestoPrime is our top-rated testosterone booster for a reason. It contains clinically effective doses of all its ingredients, comes with a lifetime money-back guarantee, and is also priced very reasonably.

Click here to buy TestoPrime from the official website now."

#2 - TestoFuel - Get Ripped and Vascular in months

TestoFuel is our go-to testosterone booster for athletes, recreational lifters, and former anabolic steroid users looking for a natural alternative to pinning. This amazing T-booster can help increase your lean muscle mass, improve your strength and shave off body fat - all at the same time.

The ingredients present in TestoFuel have all been clinically backed to support testosterone production in your body.

Why we recommend TestoFuel over Nugenix Total T?Any brand that tries to tell you that performance enhancement is solely about testosterone is talking out of their asses. It's not just about testosterone, it's about every anabolic hormone in your body working in harmony.

There are five main hormones that are responsible for muscle growth and fat loss. They are testosterone, GH (Growth Hormone), IGF-1 (Insulin-like Growth Factor), cortisol, and estrogen.

Testofuel is designed to support optimum levels of all these hormones, which is what makes it so potent for athletes.

Top 3 benefits of using TestoFuelIf you are wondering how using TestoFuel will translate into real-world benefits, here are the top three benefits you can expect:

Rapid Muscle GainsYou will be able to pack on slabs of lean muscle mass in a short period of time thanks to the potent anabolic environment created by TestoFuel. There are increased testosterone levels that's boosting muscle protein synthesis and nitrogen retention.

There are the increased GH levels that's promoting cell proliferation and differentiation. And lastly, the increased IGF-1 levels that's playing a key role in muscle hypertrophy.

Improved StrengthYou will be able to see significant improvements in strength as your muscles will be better primed for growth. The increase in testosterone will result in stronger contractions while the higher GH levels lead to a faster recovery from exercise-induced muscle damage.

Shredded PhysiqueIf you are looking to get ripped, then TestoFuel will help you get there faster thanks to the fat-burning properties of testosterone and growth hormone. The higher your T-levels are, the lower your body fat percentage will be.

Also, let's not discount the difference that the increased blood flow and perpetual muscle pumps will bring to your body.

TestoFuel CostTestoFuel comes at $65 for a month's supply. That's peanuts if you compare the cost of other T-boosters on the market that don't even come close to delivering the same results.

Plus, you don't have to worry about TestoFuel messing up your hormones as it's a natural testosterone booster.

TestoFuel - Final ThoughtsTestoFuel is a winner all the way. This potent t booster will change the way you workout in the gym. Weights become lighter, recovery becomes easier, and everything just feels easier.

The gains you'll make with TestoFuel are amazing. You will be packing on quality muscle mass in no time and getting ripped while you are at it.

Click here to buy TestoFuel from the official website now."

#3 - Prime Male - Tide through that mid-life low T crisis

Every male goes through a mid-life crisis that's caused due a dip in their primary androgenic hormone levels. This can trigger a slew of unwanted symptoms like weight gain, fatigue, low libido, and even erectile dysfunction.

Prime Male is a powerful testosterone booster that can help men deal with these issues by increasing their free and total testosterone levels.

Why we recommend Prime Male over Nugenix Total T?While recommending testosterone boosters, we look for solid evidence that goes beyond normal marketing hype.

There are several reasons why we believe that Prime Male is a better choice than Nugenix Total T. Firstly, it is the most diverse list of ingredients that we have seen in any T-booster. Secondly, the dosages of each ingredient are at the upper limit of what is considered safe and effective.

Most importantly, there are over 12 clinical studies that have been conducted on Prime Male's key ingredients, which prove beyond doubt that they can increase testosterone levels.

Top 3 benefits of using Prime MaleThere's a reason why we recommend Prime Male to every middle-aged man who's dealing with low T symptoms. Here are the top three benefits that you can expect from this testosterone booster:

Dramatic Changes in body compositionChanging your physique is not easy, especially when you're over the age of 35. Low testosterone levels make it harder to build muscle and lose fat.

Prime Male can fix the imbalances in your hormone levels, making it easier to achieve the body of your dreams.

Improved mental clarity and focusAs we age, it becomes harder to focus and retain information. This is because our testosterone levels also affect the levels of vital neurosteroids that can alter mood and motivation.

See the article here:

Nugenix Total T Reviews - Why We Are Disappointed With This T Booster - Deccan Herald

I started formally strength training on a consistent basis my sophomore year of high school thanks to a coach who pushed me to work hard. Since then, I haven't been able to put a barbell down. It has to be in my hands every day or I go a little crazy.

I also played sports throughout my childhood. I was playing every single sport under the sun and was a bigger-bodied little kid. I could not run or move or do the things that were generally expected of me. But it wasn't until high school that I realized that this body can be used in different ways.

Playing football surrounded by huge, muscular dudes, I was able to be the smaller and quicker one, and it really taught me how to rationalize that anything's trainable.

After moving to Austin for college, I didn't have much else to do. So, I worked out. I signed up for advanced weight-training class. I thought I was going in to learn how to squat, bench press, and deadlift heavier. It was so much more.

Within a month I was hooked. I just I wanted to keep training. I ended up asking the coach if I could join the powerlifting team. I ended up joining formally joining in May of 2019 and trained with them all the way through until December of 2020.

I needed it more than I realized. To walk in and be in a close space with athletes who are already experienced, who were already in a mindset that I wasn't in yet. I needed the exposure to other athletes. It's really unrivaled.

There's a popular term in weightlifting called a "garage mind," and it's really just that idea of staying gritty, getting in, and getting the work done. We don't need fancy tech. We don't need fancy movements. We just need a barbell and our program and we'll get it done. That's what we did.

Even my coach was blown away. I skipped the first day of training on hormones so I wasn't messing with my body in a million different ways on that very first day. The second day, I got back in the gym. I couldn't lift what I was lifting two days prior, though.

From there, I saw 20 to 30 percent drop in my lifting numbers. I had spent almost two years fostering this growth in Olympic weightlifting. Now it was all just melting off of me, it was it was really jarring. As the hormones went on, I got weaker. I got a little smaller, I got a little less athletic. But, I started to really feel like this is something I needed.

If I couldn't pull the barbell off the ground with perfect technique, I wasn't going to be the best I could be. It was new for me to focus on form, to not worry about the numbers anymore, but just worry about how well am I moving these numbers.

My testosterone was extremely low. It's still extremely low. So it's incredibly hard for me to make any gains, period, and especially in powerlifting. Over the course of a year, I put 20 pounds on my deadlift, and I put 10 pounds on my bencha tiny increase for me.

To experience this total drop in how I gained muscle, how I gained strength, how I move about the world, it was very jarring. I wouldn't say I was defeated by the end of my powerlifting stint, but it was brutal and it really humbles you.

That's a new thing for me too. I transitioned to back to Olympic weightlifting in spring 2022. Now I spend three to four days a week lifting a barbell. On top of that I'm doing cardio. I'm doing extra accessories.

I'm doing extra glute work to grow my backside. I didn't want to think about my glutes as a boy for my entire life. Now, as a girl, I'm realizing, Oh, there's actual muscular dysfunction back there. The stair stepper actually helps me work on that dysfunction, paired with the band work and the dumbbell work that I do.

I get to go and really truly train hard and express my athleticism throughout the week. Then, those other sessions I get to clear my head and just feel silent.

I discovered Liberation Barbell Club in Austin, which is focused on being a healthy and safe space for athletes and *all* people. The more I train there, I meet amazing people who don't see me for what I am externally.

I was worried in the first few weeks because it felt as if all the men were staring at me. But it turns out they actually were just so impressed with me because, no matter what, no matter how my numbers are dropping, I was still there training hard and being myself.

I started lifting there a week after I started hormones. To have a community and a space that allowed me to walk in in tiny booty shorts and a sports bra in the beginning of my transitionwhen I did not pass for a woman at allwas a huge step for me.

Nobody will excel in their sport if they're alone. You need people around you. Especially as a queer person and as a trans person, to have people who think the same way, who asked the same questions, who wonder about the world in the same ways, is unmatched on arrival.

I've had a lot of issues with gender dysphoria. As an athlete, I spent years idolizing other strength athletes who were always training in tiny shorts and sports bras. These women are absolutely jacked and muscular. I idolized them and I wanted to wear that too.

Early in my transition, I bought the booty shorts online from a strength athlete-specific store. It really empowered me. To be a trans woman and bring the clothes into my house that I've seen on cis women for my entire life was a huge moment for me.

In January, I ended up pulling 440 pounds at the very, very end of a meet. It was a number I've been looking for for a very long time. I was technically sound. I was so strong. My muscles were all engaged the way I needed to be.

I was so anxious, though. It was a moment I had to look at myself in the mirror and say you're here because you love doing this. You're here because you love everything about this. Right before that last deadlift, I went to the bathroom looked in the mirror and I told myself, "Go have fun. Go finish."

It was a moment that truly showed me that no matter what happens in my transition, no matter what happens in the world around me, I still will seek weight training out and work hard.

I could talk about PRs or accomplishments or big moments, but inspiring others ultimately stands out to me. I went to an event earlier in the summer in Seattle, Pull for Pride, an all-inclusive deadlift competition where anybody can come and lift. There were so many people in that room that I know for a fact would never have picked up a barbell if they didn't have that opportunity.

Those lifters told me, "You helped me you help inspire me to do this."

If everything else my life is falling apart, I can still compete. When I was struggling in my childhood and teenage years and I couldn't figure out what was wrong with me and asking myself, "Why am I depressed all the time? Why don't I feel good about myself?" Sports kept me going. Honestly, if I wasn't playing sports and lifting, I'm not sure if I would be here right now.

See the original post here:

'How Hormone Replacement Therapy Impacted My Strength Training' - Women's Health