Growth Hormone Deficiency in Children

What is growth hormone deficiency in children?

Growth hormone (GH) deficiency is when the pituitary gland doesn't make enough growth hormone. GH is needed to stimulate growth of bone and other tissues. This condition can occur at any age. GH deficiency does not affect a child's intelligence.

GH deficiency can be caused by damage to the pituitary gland or another gland called the hypothalamus. The injury can occur before birth (congenital), or during or after birth (acquired).

The pituitary gland is a pea-sized gland located at the base of the brain. Its the master endocrine gland in the body.The pituitary gland normally releases several different hormones. These hormones control growth, metabolism, blood pressure, and other body processes.

In rare cases, GH deficiency can be part of a genetic syndrome. In many cases, the cause of GH deficiency is not known (idiopathic).

A child is more at risk for GH deficiency if they have any of these:

Some children with the problem have none of the risk factors.

The main sign of GH deficiency is slower height growth than expected each year. This means a yearly growth in height of less than about 2.2 inches (5.5 cm) between ages 2 and 4, less than about 2 inches (5 cm) between ages 4 and 6, and a yearly growth of less than 1.6 inches (4 cm) for boys and less than 1.8 inches (4.5 cm) for girls. A child with GH deficiency may also have:

A younger-looking face

A chubby body build

Impaired hair growth

Delayed puberty

It's important to note that GH deficiency does not affect the child's intelligence.

The symptoms of GHdeficiency can be like other health conditions. Make sure yourchild sees their healthcare provider for a diagnosis.

To diagnose GH deficiency, your childshealthcare providerneeds to check for other conditions, such as:

Normal variations of growth, such as familial short stature

Other disorders, such as thyroid hormone deficiency or kidney disease

Genetic conditions

The healthcare provider will ask about your childs symptoms and health history and about your familys health history. They will also give your child a physical exam. Yourchild's health and growth may be checked over several months.

Your child may also have tests, such as:

Blood tests. These are done to check growth hormone and other related hormone levels. Sometimes the blood tests are done 2 to 3 hours after your child is given a medicine that would normally raise growth hormone levels.

X-ray.This test uses a small amount of radiation to make images of tissues inside the body. An X-ray may be done of the left hand and wrist. This can estimate your child's bone age. With delayed puberty or hormone problems, bone age is often less than calendar age.

CT scan. This test uses a series of X-rays and a computer to make detailed imagesof the body. A CT scan can show bones, muscles, fat, and organs. CT scans are more detailed than regular X-rays.

MRI.This test uses large magnets and a computer to make detailed images of tissues in the body without using X-rays.

Your child'shealthcare providerwill consider your child's age, overall health, and other factors when advising treatment. Your child may need to see a pediatric endocrinologist. This is a doctor with extra training in treating children with hormone problems. This specialist will also have the best equipment to accurately measure your child's growth from month to month.

Treatment may involve daily injections of synthetic growth hormone. Results are often seen as soon as 3to4 months after treatment starts. The treatment lasts several years, usually until late puberty when growing is finished. The earlier the treatment is started, the better the chances that a child will have a normal or near-normal adult height that matches their family pattern.

Not all children respond well to growth hormone treatment. GH therapy does not make a person taller than their parents. Your child may have other treatments depending on what causes the deficiency.

If untreated, GH deficiency can cause a child to not reach their normal adult height.

Children who are shorter than their peers may have poor self-esteem or depression. Its important to talk about these problems with your child and your child's healthcare provider. The provider can recommend counseling or support groups for you and your child.

Talk with your child's healthcare provider about your child's potential adult height. Work with your child's healthcare providers to create an ongoing plan to manage your childs condition.

Talk with your childs healthcare provider if you are concerned about your child's growth.

Growth hormone (GH) deficiency is when the pituitary gland doesn't make enough growth hormone. GH is needed to stimulate growth of bone and other tissues.

GH deficiency does not affect a child's intelligence.

The main sign of GH deficiency is slowed height growth each year than expected. A child with GH deficiency may also have a younger-looking face and a chubby body build.

Treatment may include daily injections of synthetic growth hormone. Results are often seen as soon as 3to4 months after treatment starts. The treatment lasts several years, usually until late puberty when growing is finished.

The earlier the treatment is started, the better the chances that a child will have a normal or near-normal adult height that matches their family pattern.

If untreated, GH deficiency can cause a child to not reach their normal adult height.

Tips to help you get the most from a visit to your childs healthcare provider:

Know the reason for the visit and what you want to happen.

Before your visit, write down questions you want answered.

At the visit, write down the name of a new diagnosis and any new medicines, treatments, or tests. Also write down any new instructions your provider gives you for your child.

Know why a new medicine or treatment is prescribed and how it will help your child. Also know what the side effects are.

Ask if your childs condition can be treated in other ways.

Know why a test or procedure is recommended and what the results could mean.

Know what to expect if your child does not take the medicine or have the test or procedure.

If your child has a follow-up appointment, write down the date, time, and purpose for that visit.

Know how you can contact your childs provider after office hours. This is important if your child becomes ill and you have questions or need advice.

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Growth Hormone Deficiency in Children